Wodwala woyamba yemwe ali ndi vuto lakumva chifukwa cha ukalamba amalandira chithandizo chatsopano

ACOU085 yaperekedwa kwa wodwala woyamba yemwe ali ndi vuto lakumva lokhudzana ndi zaka (presbycusis) mu phunziro lachipatala la Phase 1b ku Germany. Kuwunika koyambirira kwa odwala omwe akufanana ndi zonse zomwe zili mkati / kusapezeka kwa mayesero omwe akupitilira pafupifupi kutha. Kuphatikiza pa cholinga cha phunziroli, kuyesa chitetezo ndi kulekerera kwa munthu yemwe akufuna kugwiritsa ntchito mankhwala osokoneza bongo kwa anthu kwa nthawi yoyamba, kuyesedwa kosiyanasiyana kokhazikika komanso kofuna kumva akuchitidwa kuti athandizire kufufuza zomwe akufuna.

ACOU085 ndi eni yaing'ono-molekyulu, otoprotective mankhwala phungu kuti modulates bwino kumatanthauza maselo chandamale makamaka amasonyezedwa mu maselo a mkati khutu, otchedwa akunja tsitsi maselo (OHC). ACOU085 imadziwika ndi machitidwe apawiri apadera: molekyulu imayambitsa kupititsa patsogolo kwakumva komanso kutetezedwa kwanthawi yayitali kwa ma OHC osiyanitsidwa. Mu Disembala 2021, Acousia Therapeutics idapatsidwa CTA ndi Germany BfArM kuti ayambitse kuyesa kwachipatala koyamba mu Gawo 1b kwa ACOU085.

"Chotsatira chotsatira cha Acousia's otoprotective drug candidate ACOU085 mu maphunziro a odwala presbycusis ndi chizindikiro chofunika kwambiri pa njira yathu yopangitsa kumva kumva kukhala matenda ochiritsira," akutero Dr. Tim Boelke, Chief Executive Officer ndi Chief Medical Officer wa kampaniyo.

"Ndili wonyadira kwambiri kuti ntchito yathu yoyendetsedwa ndi malingaliro, yasayansi tsopano ikupita kuchipatala patatha zaka 6 titayambitsa pulogalamu yachitukuko ya mankhwala a novo pamutu watsopano wa mankhwala osokoneza bongo," akuwonjezera Hubert Löwenheim, Pulofesa. Wapampando wa dipatimenti ya Otolaryngology-Head & Neck Surgery ya University of Tübingen ndi Acousia Therapeutics co-founder.