FDA ivomereza mapiritsi atsopano a Pfizer kuchiza COVID-19

Lero, a US Administration ndi Mankhwala Osokoneza Bongo (FDA) adapereka chilolezo chogwiritsa ntchito mwadzidzidzi (EUA) cha Pfizer's Paxlovid (mapiritsi a nirmatrelvir ndi mapiritsi a ritonavir, ophatikizidwa kuti agwiritsidwe ntchito pakamwa) pochiza matenda a coronavirus ofatsa mpaka pang'ono (COVID-19) mwa akulu ndi odwala ana (wazaka 12 ndi kupitilira zolemera ma kilogalamu 40) kapena pafupifupi mapaundi 88) okhala ndi zotsatira zabwino zakuyezetsa mwachindunji kwa SARS-CoV-2, komanso omwe ali pachiwopsezo chachikulu cha COVID-19, kuphatikiza kugona m'chipatala kapena kufa.

Paxlovid imapezeka ndi mankhwala okha ndipo iyenera kukhazikitsidwa posachedwa atapezeka ndi COVID-19 komanso pasanathe masiku asanu zizindikiro zayamba.

"Chilolezo chamasiku ano chikubweretsa chithandizo choyamba cha COVID-19 chomwe chili ngati piritsi lomwe limamwedwa pakamwa - sitepe yayikulu yolimbana ndi mliri wapadziko lonse lapansi," atero Patrizia Cavazzoni, MD, director of the FDA's Center for Drug Evaluation and Research. "Chilolezochi chimapereka chida chatsopano chothana ndi COVID-19 panthawi yofunika kwambiri pa mliriwu pomwe mitundu yatsopano ikutuluka ndikulonjeza kuti chithandizo chamankhwala oletsa ma virus chizitha kupezeka kwa odwala omwe ali pachiwopsezo chachikulu cha COVID-19."

Pfizer's Paxlovid sanaloledwe kuti asadziwike kapena apewe kukhudzana ndi COVID-19 kapena kuyambitsa chithandizo kwa omwe akufunika kuti agoneke m'chipatala chifukwa cha COVID-19 yovuta kapena yovuta. Paxlovid sicholowa m'malo mwa katemera wa anthu omwe akulimbikitsidwa katemera wa COVID-19 komanso mlingo wowonjezera. A FDA avomereza katemera m'modzi ndikuloleza ena kuti aletse COVID-19 ndi zotsatira zoyipa zachipatala zomwe zimakhudzana ndi matenda a COVID-19, kuphatikiza kugona m'chipatala ndi imfa. The FDA imalimbikitsa anthu kuti alandire katemera ndi kulandira chithandizo ngati akuyenera.

Paxlovid imakhala ndi nirmatrelvir, yomwe imalepheretsa puloteni ya SARS-CoV-2 kuti aletse kachilomboka kuti lisabwereze, komanso ritonavir, yomwe imachepetsa kuwonongeka kwa nirmatrelvir kuti ithandizire kukhalabe m'thupi kwa nthawi yayitali kwambiri. Paxlovid amaperekedwa ngati mapiritsi atatu (mapiritsi awiri a nirmatrelvir ndi piritsi limodzi la ritonavir) amatengedwa pakamwa kawiri tsiku lililonse kwa masiku asanu, pamapiritsi 30 okwana. Paxlovid saloledwa kugwiritsidwa ntchito kwa masiku opitilira asanu motsatizana.