Kupambana Kwambiri kwa Clinical Mitral Valve Replacement

Wodwalayo ndi mkazi wazaka 74 yemwe posachedwapa adagonekedwa m'chipatala chifukwa cha kulephera kwa mtima kumanzere, komanso kupitilira kwa matenda a atrial fibrillation, matenda oopsa, matenda a shuga ndi matenda ena azachipatala. Opaleshoniyo idayenda bwino ndikuyika bwino komanso zotsatira zabwino pambuyo panjira. Kubwezeretsa kwa mitral valve kunachotsedwa mwamsanga pambuyo pa ndondomekoyi popanda kulepheretsa LVOT. Wodwalayo wakhala akuchira bwino, ndipo adasamutsidwa kuchokera ku chipinda cha odwala kwambiri (ICU) kupita ku wadi wamba tsiku lotsatira ndi ntchito yabwino ya mtima. Anatulutsidwa m'chipatala pa December 30, 2021. Kuchita bwino kumeneku kunayala maziko olimba achipatala cham'tsogolo cha Peijia's HighLife TSMVR system ku China.              

"Mapangidwe apadera a 'Valve-in-Ring' amapangitsa kuti ikhale yoyenera pamitundu yambiri ya mitral valve anatomy." adatero Pulofesa Mao Chen. "Odwala ambiri sangafunikire kutsekedwa kwa vuto la septal pambuyo pobowoleredwa ndi 30F yoperekera catheter, ndipo kuthekera kwazovuta zam'mitsempha ndizochepa. Njirayi imachitika pansi pa DSA yokhazikika molumikizana ndi echocardiogram, yomwe ingalimbikitse kukhazikitsidwa kwaukadaulo uwu. Ndikukhulupirira kuti ukadaulo uwu ungagwiritsidwe ntchito pazachipatala zambiri posachedwa kuti athandize odwala omwe ali ndi mitral regurgitation. "

Ukadaulo wa HighLife umapereka zida zapadera zochizira kusakwanira kwa mitral valve

Transcatheter Mitral Valve Replacement ("TMVR") yakhala ikuyenda bwino pantchito yochizira matenda amtima. Maphunziro oyambirira ofufuza atsimikizira kuti teknolojiyi ndi yotetezeka komanso yothandiza. TMVR ndiyoyenera kutengera mawonekedwe a mitral regurgitation ("MR"). Ikhoza kuchepetsa kapena kuthetseratu regurgitation ndipo zotsatira za odwala nthawi zambiri zimakhala zokhazikika. Kuphatikiza apo, TMVR ndiyosavutitsa kwambiri ndipo imatha kuchitidwa kwa okalamba kapena odwala omwe ali pachiwopsezo chachikulu poyerekeza ndi olowa m'malo mwa opaleshoni.

Komabe, gawo la Mitral Valve Replacement likukumanabe ndi zovuta zambiri zaukadaulo, kuphatikiza kupeza malo omwe mukufuna, kukhazikika komanso kuwopsa kwa kutayikira kwa paravalvular ("PVL") ndi kutsekereza kwa LVOT. Njira zambiri zomwe zilipo kale ndi za transapical kapena nangula pogwiritsa ntchito mphamvu yozungulira. Transapical TMVR ingayambitse kufooka kwa minofu ya khoma lamanzere la ventricular kapena ngakhale kusakhazikika kwa kumenyedwa kwa ventricular yakumanzere chifukwa cha kudulidwa kwa opaleshoni. Kukhazikika kwa TMVR ndi mphamvu yozungulira kungayambitse kukula kwa vavu yaikulu ndi kuvutika popereka, zomwe zingathe kutsogolera kumanzere kwa ventricular reverse remodeling. Dongosolo la HighLife TSMVR limagwiritsa ntchito lingaliro lapadera la "Valve-in-Ring" lomwe limatha kuthana ndi zovuta izi. Dongosololi limalekanitsa valavu kuchokera ku mphete yake yomangira ndipo imapereka zigawo ziwirizo kudzera mu mtsempha wa chikazi ndi mtsempha wachikazi motsatira.

Ndi njira zitatu zosavuta. Choyamba, chingwe chowongolera chimayikidwa mozungulira timapepala ta valavu komwe wodwalayo amakhala komanso chordae. Kachiwiri, mphete yolumikizira imayikidwa. Pomaliza, valavu yodzikulitsa yokha ya bovine pericardial imatulutsidwa kudzera mu transseptal access. Vavu yoperekedwa imazikika polumikizana kenako kufika pamalo ofanana ndi mphete yomwe idayikidwapo kale. Izi zimathandiza kuti valavu ikhalebe pamalo okhazikika popanda kuwononga minofu yoyambirira. Njirayi ndi yophweka chifukwa dongosololi ndi lodzikonda komanso lodzigwirizanitsa. Mapangidwe a makinawa amathandizira kuchepetsa chiwopsezo cha kutayikira kwa paravalvular ndikuchepetsa kukula kwa catheter. Njirayi imatha kumalizidwa bwino pogwiritsa ntchito chithandizo cha teleproctoring.

Peijia Medical adawonetsa kuthekera kwake mu mgwirizano wapadziko lonse lapansi komanso ukatswiri waukadaulo

Mu Disembala 2020, Peijia Medical idachita mgwirizano wa laisensi ndi HighLife SAS, kampani yaku France ya zida zamankhwala, malinga ndi zomwe HighLife SAS idapatsa Peijia Medical chilolezo chokhacho chopanga, kupanga ndi kugulitsa zinthu zina za TMVR mdera la Greater China. Kusintha kwaukadaulo kumeneku kunamalizidwa m'gawo lachitatu la 2021. Zopanga zam'deralo zokhala ndi miyezo yapamwamba kwambiri ku China zakhazikitsidwa: chipangizo cha HighLife chopangidwa ndi Peijia Medical chidapambana mayeso onse owonetsa kuti akufanana kwambiri ndi HighLife SAS. Kuyambira chiyambi cha kusamutsidwa kwaukadaulo mpaka kuyikidwa koyamba mu kafukufuku wazachipatala ku China, Peijia Medical idatenga zosakwana chaka chimodzi kuti amalize ntchitoyi yomwe idawonetsa kuthekera kwake pakugwirizanitsa mayiko ndi ukatswiri waukadaulo.

Pofuna kufulumizitsa kugwiritsa ntchito ukadaulo wotsogola padziko lonse lapansi pothandiza odwala a MR ku China, alangizi a Peijia Medical, Pulofesa Nicolo Piazza ndi Pulofesa Jean Buithieu ochokera ku McGill University Medical Center ku Canada, komanso akatswiri aukadaulo a HighLife SAS anagwira ntchito limodzi ndi Peijia. Zachipatala kukonzekera mayesero azachipatala awa. Maphunziro angapo okhudzana ndi zida ndi machitidwe azachipatala adachitika ndipo akatswiri a Cardiologist ku China nawonso adatenga nawo gawo pakuchitapo kanthu kuti awonetsetse kuti kuyikidwa bwino.

Dr. Nicolo Piazza ankaganizira kwambiri za mgwirizano uwu ndi kuyika bwino. "Ndili wokondwa komanso wolemekezeka kuthandizira Pulofesa Mao Chen ndi gulu lake kutali kuti akwaniritse njira ya HighLife TSMVR ndikugawana luso langa. Ndinadabwitsidwanso ndi luso lapamwamba komanso mgwirizano wachinsinsi wa Pulofesa Mao Chen ndi gululo. Ndine wokondwa kwambiri kuyika bwino kwa dongosolo loyamba la TSMVR ku Asia. Ndinkakhulupirira kuti njira ya HighLife TSMVR ikhoza kupindulitsa odwala ambiri m'tsogolomu, ndipo ndikuyembekeza chitukuko champhamvu pazochitika za mitral valve interventional therapy. "

Kutsatira masomphenya ake a "Kudzipereka Pamtima, Kulemekeza Moyo", Peijia Medical imayesetsa kupititsa patsogolo umoyo wa odwala kupyolera mu kufufuza kwaumisiri ndi kulimbikira kwatsopano. "Tawona maphunziro ochulukirapo a momwe ukadaulo wa TMVR umalimbana ndi zovuta zomwe zimachokera ku zovuta za mitral valve komanso kuopsa kwa matendawa. Kuyesetsa mosalekeza kumeneku kukuwonetsa kufunika kwa chithandizo cha TMVR, "adatero Dr. Michael Zhang Yi, Wapampando ndi CEO wa Peijia Medical. "Ngakhale njira ya transseptal ndi njira yokondedwa ndipo imapambana m'njira zambiri, matekinoloje ambiri omwe alipo a TMVR amagwiritsabe ntchito njira yodutsa. HighLife SAS ndi mtsogoleri wapadziko lonse muukadaulo wa TSMVR, wokhala ndi zotulukapo zoyembekezeka zachipatala zomwe zidasindikizidwa mu TCT 2021 ndi PCR London Valves 2021. Tithokoze Pulofesa Mao Chen ndi Pulofesa Nicolo Piazza chifukwa cha mgwirizano wawo pakuyika koyamba kwa Peijia's HighLife System, kuyika kopambana. yalimbitsanso chidaliro chathu pochiza matenda a mitral valve ndiukadaulo wocheperako wolowera. Peijia Medical ipitiliza kudzipereka kwathu pazatsopano, ndikuyembekeza kuti odwala ambiri aku China omwe akudwala matenda a mitral valve angapindule ndi kupita patsogolo kwaukadaulo kotere. ”

Dongosolo la Peijia's HighLife TSMVR limayimira chithandizo chamakono cha mitral valve interventional, chomwe chidzasintha kwambiri moyo wa odwala aku China omwe ali ndi MR kwambiri. Chikhulupiriro cha Peijia Medical "choika moyo wa odwala ndi chitetezo patsogolo popititsa patsogolo chitukuko chamankhwala osavutikira kwambiri kunyumba ndi kunja" sichinasinthe.