"Gulu la SNIPR BIOME ndilokondwa ndi chochitika chofunikirachi, ndipo tikuyembekezera kuyambitsa mayesero azachipatala ku US kumapeto kwa chaka chino, kuyesa luso lathu lapadera la CRISPR. SNIPR001 ndi chuma chathu chomwe chapita patsogolo kwambiri, ndipo timanyadira kwambiri khama la gulu lomwe latibweretsa kuno "akutero Dr. Christian Grøndahl, Co-founder & CEO.
Kuyesa kwachipatala kungapangitse njira ya mtundu watsopano wa chithandizo cholondola kuti usankhire E. coli mwa odwala khansa omwe ali ndi hematological malignancies - omwe ndi khansa yomwe imakhudza magazi, mafupa a mafupa, ndi ma lymph nodes. Odwalawa ali pachiwopsezo chowonjezereka cha matenda owopsa a m'magazi chifukwa cha matendawa, chithandizo chamankhwala chamankhwala ndipo, chofunikira kwambiri, kutengera kachilombo ka HIV kuchokera m'matumbo, momwe E. coli ndi m'modzi mwa omwe amathandizira kwambiri pakuyambitsa matenda.
SNIPR001 ikufuna kutsata mabakiteriya a E. coli m'matumbo, ndipo potero amalepheretsa kusamutsidwa kwa mabakiteriyawa kupita m'magazi, ndikusiya mabakiteriya a commensal mu microbiome ya wodwalayo osakhudzidwa. Njira yogwiritsira ntchito SNIPR001 ikugwiritsa ntchito njira yatsopano yogwiritsira ntchito teknoloji yathu ya CRISPR/Cas pofuna kuthetsa mabakiteriya a E. coli m'matumbo. Njira yolondolayi ingasinthe momwe matenda a E. coli amapewedwera ndi kuthandizidwa, makamaka m'chipinda cha khansa.
Masiku ano, palibe mankhwala ovomerezeka a prophylactic therapy potengera izi.
"Kutengera chidziwitso chathu chachipatala chisanachitike ndi SNIPR001 timakhulupirira kuti ukadaulo wathu uli ndi kuthekera kwakukulu popanga mankhwala a CRISPR a mawa polimbana ndi matenda oopsa komanso kuwongolera matenda okhudzana ndi tizilombo toyambitsa matenda," akutero Dr. Milan Zdravkovic, Chief Medical Officer ndi Mutu. R&D ku SNIPR Biome. "Ndikuchulukirachulukira kwa anti-microbial resistance pakufunika mwachangu ofuna mankhwala atsopano kuti azichiza mabakiteriya opatsirana, monga E. coli, ndipo tikuthokoza chifukwa cha mgwirizano ndi bungwe lopanda phindu, CARB-X pa SNIPR001".
SNIPR001 ndiye woyamba mwa anthu ambiri omwe akufuna kuchiza, monga momwe Dr. Christian Grøndahl adafotokozera: "Tikumanga mapaipi amphamvu azinthu zatsopano za CRISPR ndipo tili ndi chidwi ndi matenda opatsirana, mgwirizano ndi MD Anderson Cancer Center pa immuno-oncology, komanso ndi Novo Nordisk pakugwiritsa ntchito matekinoloje osintha ma gene pa microbiome. Ndife okondwa kufufuza momwe tingathere luso lathu la CRISPR mtsogolomu ".
