Kafukufuku watsopano amabweretsa chiyembekezo kwa odwala tinnitus

Kafukufuku wodziyimira pawokha wochokera ku Germany amatsimikizira kuti bimodal neuromodulation imatha kuchepetsa kwambiri zizindikiro za tinnitus muzochitika zenizeni zachipatala.

Kampani yachipatala ya ku Ireland, Neuromod Devices Ltd. (Neuromod), yalandira zotsatira za kafukufuku wodziimira pawokha wochitidwa ku German Hearing Center (DHZ) ku Hannover Medical School, yomwe inapeza kuti 85% ya odwala tinnitus adachepetsa zizindikiro za tinnitus. (kutengera chiwerengero cha Tinnitus Handicap Inventory [i] pa odwala 20) mukamagwiritsa ntchito chipangizo cha Lenire.

Kafukufukuyu adawonetsa kuti masabata asanu ndi limodzi mpaka 12 a chithandizo chogwiritsa ntchito Lenire, chipangizo cha bimodal neuromodulation chopangidwa ndi Neuromod chomwe chimapereka mphamvu yomveka komanso yamagetsi ya lilime, imatha kukwaniritsa bwino lomwe pakuwongolera kwamphamvu kwazizindikiro za tinnitus muzochitika zenizeni zachipatala.

Phunzirolo linatsogoleredwa ndi Dr. Thomas Lenarz, Anke Lesinski-Schiedat, ndi Andreas Buechner ochokera ku Dipatimenti ya Otolaryngology ku Hannover Medical School, Germany.

Zotsatira izi zidasindikizidwa posachedwapa m'magazini yasayansi yapamwamba kwambiri, Kulimbikitsa Ubongo[ii].

Deta yeniyeni yeniyeni ikugwirizana ndi zotsatira za mayesero akuluakulu a zachipatala a Neuromod (TENT-A1), omwe anaphatikizapo otenga nawo mbali 326. Kuyesa kwa TENT-A1, zomwe zotsatira zake zidasindikizidwa mu Okutobala 2020[iii], zidawonetsa kuti 86.2% ya omwe adatsatira chithandizo chamankhwala adanenanso zakusintha kwazizindikiro zawo za tinnitus patatha milungu 12 pogwiritsa ntchito Lenire.

Phunziro la Hannover linali ndi nthawi yayitali ya chithandizo (masabata a 6-12) ndipo adawona kusintha kwakukulu (kuchepa) kwa chiwerengero cha THI cha mfundo za 10.4, zomwe zimaposa kusiyana kwakukulu kwachipatala kwa mfundo za 7. Deta yeniyeniyi yochokera ku phunziro la Hannover ikugwirizana ndi kafukufuku wa TENT-A1, yemwe adawona kusintha kofanana pambuyo pa masabata a 6 a chithandizo ndipo adakwaniritsa mfundo zonse za 14.6 pambuyo pa masabata onse a 12 a chithandizo. Kuphatikiza apo, panalibe zochitika zoyipa zokhudzana ndi chithandizo zomwe zidanenedwa.

Lenire amagwira ntchito popereka kugunda kwamagetsi pang'ono ku lilime, kudzera m'chigawo chapakamwa chotchedwa 'Tonguetip', kuphatikiza ndi mawu omwe amaseweredwa kudzera pa mahedifoni kuti ayendetse kusintha kwanthawi yayitali kapena neuroplasticity muubongo pochiza tinnitus.

Kuyesa kwachipatala kwa TENT-A1, komwe kudakhudza anthu 326 ku Ireland ndi Germany, kunawonetsa mphamvu ya Lenire pakuwongolera zizindikiro za tinnitus. 86.2% ya omwe adatsatira chithandizo chamankhwala adanenanso kusintha kwa zizindikiro zawo za tinnitus pambuyo pa nthawi ya chithandizo cha masabata a 12[iv]. Pambuyo pa miyezi ya 12 pambuyo pa chithandizo, 80.1% ya omwe adatsatira chithandizo chamankhwala adapitirizabe kusintha zizindikiro zawo za tinnitus.

Kafukufuku wa TENT-A1 akuyimira limodzi mwamayesero akulu kwambiri komanso atali kwambiri omwe adatsatiridwapo m'munda wa tinnitus ndipo inali nkhani yakutsogolo ya nyuzipepala yasayansi ya Science Translational Medicine mu Okutobala 2020.

Neuromod imagwira ntchito mwaukadaulo wosagwiritsa ntchito neuromodulation ndipo idapanga ndikupanga Lenire, yomwe yakhala ikugwiritsidwa ntchito pochiza odwala omwe ali ndi vuto la tinnitus kuyambira 2019.