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Kupanga Kwakukulu kwa Oral COVID-19 Antiviral Mankhwala ndi Mayeso

Written by mkonzi

Pakadali pano, COVID-19 ikadali mliri padziko lonse lapansi. Maonekedwe apamwamba a mitundu ya Delta ndi Omicron ndiwochulukira, zomwe zimapangitsa kuti kuthekera kwawo kofalitsira kukhale kopitilira patsogolo. Pakati pa mafunde obwerezabwereza a COVID-19, kuwonjezera pa katemera wa COVID-19, kupanga mankhwala apakamwa a COVID-19 komanso njira zoyesera zachangu, zosavuta komanso zotsogola zakhalanso kufunikira kwatsopano popewa komanso kuwongolera miliri. Viva Biotech Holdings XLement, yokhazikitsidwa ndi Viva BioInnovator, yadzipereka pakupanga mankhwala akumwa a COVID-19 ndi kuyezetsa kachilombo, zomwe zikuthandizira polimbana ndi mliri wa COVID-19.

Jan 2022, Medicines Patent Pool (MPP) idalengeza kuti yasaina mapangano ndi makampani angapo opanga ma generic kuphatikiza Zhejiang Langhua Pharmaceutical Co., Ltd., wocheperako wa Viva biotech holdings popanga mankhwala oletsa antiviral oral COVID-19 molnupiravir ndi perekani m'maiko 105 omwe ali ndi ndalama zotsika ndi zapakati (LMICs) kuti athe kupeza mwayi wapadziko lonse wa molnupiravir ndikuthandizira kupewa ndi kuwongolera miliri. Makampani asanu aziyang'ana kwambiri kupanga zopangirazo, makampani 13 azipanga zopangira zonse komanso mankhwala omalizidwa ndipo makampani 9 apanga mankhwala omalizidwa.

The Medicines Patent Pool (MPP) ndi bungwe la United Nations lothandizidwa ndi boma la zaumoyo lomwe likuyesetsa kuwonjezera mwayi wopeza, ndikuthandizira kupanga, mankhwala opulumutsa moyo kwa mayiko omwe ali ndi ndalama zochepa komanso zapakati. MPP ndi MSD, dzina la tradename la Merck & Co., Inc Kenilworth NJ USA inasaina pangano lachiphaso modzifunira mu Oct 2021. Mogwirizana ndi mgwirizanowu, MPP, kudzera mu chilolezo choperekedwa ndi MSD, idzaloledwa kupititsa patsogolo laisensi yosakhala yokhayokha. malayisensi kwa opanga ndikusintha malo opangira zinthu kuti apereke molnupiravir yotsimikizika kumayiko omwe ali ndi Licence ya MPP, malinga ndi chilolezo cham'deralo.

Molnupiravir (MK-4482 ndi EIDD-2801) ndi njira yofufuzira, yoyendetsedwa pakamwa ya analogi yamphamvu ya ribonucleoside yomwe imalepheretsa kubwereza kwa SARS-CoV-2 (choyambitsa COVID-19). Molnupiravir yomwe MSD ikupanga mogwirizana ndi Ridgeback Biotherapeutics, ndiye mankhwala amkamwa oyamba oletsa ma virus omwe amapezeka pamankhwala a COVID-19. Zambiri kuchokera mu Gawo 3 MOVe-OUT zawonetsa kuti kulandira chithandizo msanga ndi molnupiravir kumachepetsa kwambiri chiwopsezo chogonekedwa m'chipatala kapena kufa pachiwopsezo chachikulu, akuluakulu osatemera omwe ali ndi COVID-19.

Malinga ndi MPP, makampani omwe adapatsidwa chiphasochi adawonetsa bwino kuthekera kwawo kukwaniritsa zofunikira za MPP zokhudzana ndi kuchuluka kwa kupanga, kutsata malamulo, komanso kuthekera kokwaniritsa miyezo yapadziko lonse lapansi yamankhwala otsimikizika. Chilolezo choperekedwa ku Langhua Pharmaceutical ndi MPP chikuyimira kutsimikizika kwakukulu ndikuzindikirika pakukula kwake ndi kukulitsa ma API, kukhazikika kwazinthu, GMP ndi dongosolo la EHS.

WTM London 2022 zidzachitika kuyambira 7-9 Novembala 2022. Lowetsani tsopano!

Pa Marichi 2, 2022, Xlement, kampani yodzipereka ya NanoSPR biochip ndi zida za biotech yomwe idayikapo kale ndalama ndi Viva BioInnovator, idalandira chidziwitso chopereka chidziwitso kuchokera ku Unduna wa Sayansi ndi Ukadaulo waku People's Republic of China. Ntchito yake "R&D ndi Mass Production ya NanoSPR COVID-19 Particle Test Kit" ndi imodzi mwama projekiti ofunikira a "Public Safety Risk Prevention and Control and Emergency Response Technology and Equipment" yomwe imagwira ntchito yofunika kwambiri pa COVID-19- Kafukufuku wokhudzana ndi sayansi akupitilira ku China. Ndi chiphaso chake choyendera bwino, Xlement's COVID-19 Test Kit nayonso yatsimikiziridwa ndi European Union CE kuti ipange zochuluka mtsogolo ndipo iyamba kugwiritsidwa ntchito posachedwa.

Pogwiritsa ntchito ukadaulo wapadera wa NanoSPR chip, Xlement adapanga zida zoyeserera za tinthu tating'ono ta COVID-19, zomwe zimalola kuyesa kwa ma antigen angapo kwa zitsanzo 96 mkati mwa mphindi 15, ndipo kukhudzika kuli pafupi kuyesa antigen imodzi. Njirayi imasonyeza ubwino waukulu poyerekeza ndi njira zomwe zilipo kale za mavairasi a nucleic acid kuyesa: zikhoza kugwiritsidwa ntchito podziyesa kunyumba, zimafupikitsa nthawi yoyesera kwambiri, motero, zimachepetsa kwambiri mtengo wa kuyesa ma reagents ndi ntchito. Ndi kutengera ukadaulo wa NanoSPR pakuyesa kwa COVID-19 kopangidwa ndi Xlement, tikuyembekeza kuwona kuzindikirika kwachangu kwa zitsanzo zomwe akuwakayikira ndikuwunika mwachangu pamalopo pamlingo waukulu.

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mkonzi

Mkonzi wamkulu wa eTurboNew ndi Linda Hohnholz. Amakhala ku eTN HQ ku Honolulu, Hawaii.

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