Mankhwala a cannabis ochepetsa ma opioid amagwiritsidwa ntchito kwa odwala omwe ali ndi ululu wosaneneka

Kupereka mwayi kwa odwala omwe ali ndi ululu wammbuyo komanso osteoarthritis (OA) ku cannabis yachipatala kungachepetse kapena kuthetseratu kugwiritsa ntchito ma opioid pakuwongolera ululu, malinga ndi maphunziro awiri omwe adachitika pamsonkhano wapachaka wa 2022 wa American Academy of Orthopedic Surgeons (AAOS). Motsogoleredwa ndi Principal Investigator Asif M. Ilyas, MD, MBA, FAAOS, maphunzirowa adawonetsanso kuti ululu ndi ubwino wa moyo umakhala wabwino pambuyo poti odwala atsimikiziridwa kuti ali ndi cannabis yachipatala.     

Anthu mamiliyoni makumi asanu aku America amavutika ndi ululu wosaneneka wosagwirizana ndi khansa, yomwe nthawi zambiri imathandizidwa ndi opioids. Komabe, pakufunika njira zina zochiritsira. Mu 2019, anthu pafupifupi 10.1 miliyoni azaka 12 kapena kupitilira apo adagwiritsa ntchito ma opioid molakwika mu 2019, ii komanso kuledzera kwa opioid kumakhalabe kokwera kwambiri. Kugwiritsiridwa ntchito kwa cannabis yachipatala kwafufuzidwa ngati njira ina yochizira ma opioid, koma kafukufuku wina akufunika kuti awonenso mphamvu, madontho, ndi momwe angakhudzire kugwiritsa ntchito opioid pakuwongolera ululu.

"Pakachitika vuto la opioid panopa, tiyenera kuzindikira njira zina zomwe zingachepetse kudalira opioids pofuna kuthetsa ululu," adatero Dr. Ilyas, mtsogoleri wa pulogalamu ya mgwirizano wa opaleshoni ya manja ndi apamwamba ku Rothman Orthopedic Institute ndi pulofesa wa opaleshoni ya mafupa. ku Thomas Jefferson University Hospital ku Philadelphia. "Pakadali pano, sitikulimbikitsa kugwiritsa ntchito mankhwala osokoneza bongo nthawi zonse kapena kunena kuti ndi njira yabwinoko, koma maphunziro athu akuwonetsa kuthekera."

Kugwiritsa Ntchito Cannabis Pakupweteka Kwambiri Kwam'mbuyo ndi Odwala OA

Maphunziro awiriwa adawunikiranso zambiri zamankhwala odzaza a opioid odzazidwa ndi odwala omwe akudwala msana komanso OA omwe adatsimikiziridwa kuti apeza cannabis yachipatala pakati pa February 2018 ndi Julayi 2019. Pafupifupi ma morphine milligram ofanana (MME) patsiku lamankhwala opioid adadzaza miyezi isanu ndi umodzi asanapezeke. ku chamba chachipatala kuyerekezedwa ndi miyezi isanu ndi umodzi pambuyo poti odwala adapeza mwayi.

Deta yosatha ya musculoskeletal non-cancer back pain idawonetsa:

• Kutsika kwakukulu kwa avareji ya MME patsiku pambuyo polembera mankhwala a chamba, kuchokera pa 15.1 mpaka 11.0 (n=186).

• 38.7% ya odwala adatsika mpaka ziro MME patsiku.

• Odwala omwe anayamba pa zosakwana 15 MME patsiku ndi oposa 15 MME patsiku anali ndi kuchepa kwakukulu, kuchokera ku 3.5 mpaka 2.1 (n=134) ndi 44.9 mpaka 33.9 (n=52). Maperesenti a odwala omwe adatsikira ku ziro MME patsiku m'maguluwa anali 48.5% ndi 13.5%, motsatana.

• Poyerekeza ndi zoyambira (miyezi itatu, isanu ndi inayi, ndi isanu ndi inayi), odwala adanenanso kuti akuwonjezeka kwambiri, nthawi zambiri, komanso ntchito za tsiku ndi tsiku pambuyo pogwiritsira ntchito mankhwala osokoneza bongo.

• Odwala omwe adagwiritsa ntchito njira ziwiri kapena zingapo zoyendetsera cannabis yachipatala adawonetsa kuchepa kwakukulu kwa MME patsiku, kuchokera ku 13.2 mpaka 9.5 (n = 76).

Pochiza OA, zotsatira za odwala zidawunikidwa patatha miyezi itatu, sikisi, ndi isanu ndi inayi pambuyo pakugwiritsa ntchito mankhwala a cannabis. Atapeza cannabis yachipatala, kafukufukuyu adawonetsa:

• Panali kuchepa kwakukulu kwa chiwerengero cha MME pa tsiku la mankhwala odzazidwa ndi odwala, kuchokera ku 18.2 mpaka 9.8 (n = 40). Kutsika kwapakati pa MME patsiku kunali 46.3%.

• Odwala omwe adatsika mpaka ziro MME patsiku anali 37.5%.

• Kupweteka kwa odwala kunachepa kwambiri, kuchokera ku 6.6 (n = 36) mpaka 5.0 (n = 26) ndi 5.4 (n = 16), pa miyezi itatu ndi isanu ndi umodzi, motero.

• Kuchuluka kwa moyo wa Global Physical Health kunakula kwambiri, kuchokera ku 37.5 mpaka 41.4, pa miyezi itatu.

"Kafukufuku wathu akuwonetsa kuti cannabis yachipatala ikhoza kukhala chithandizo chamankhwala chothandizira kupweteka kwa msana ndi osteoarthritis, zomwe zingathandize kuchepetsa kudalira opioids," adatero Dr. Ilyas. "Komabe, kafukufuku wowonjezera akufunika kuti mumvetsetse bwino njira ndi ma frequency, zovuta zomwe zingachitike, komanso zotsatira zanthawi yayitali zakugwiritsa ntchito chamba chachipatala. Pakadali pano, olembera ayenera kugwiritsa ntchito zisankho zomwe amagawana ndi odwala awo poganizira zachipatala chamankhwala opweteka kwambiri a minofu ndi mafupa. "