Mogwirizana ndi dongosololi, GoldenBiotech idzapereka lipoti lomaliza la kafukufuku wachipatala ndi zolemba zokhudzana ndi R&D ku US FDA kuti ikalembetse chilolezo chogwiritsa ntchito mwadzidzidzi (EUA) kwa Antroquinonol (HOCENA®).
Mlanduwu ndi kafukufuku wa Gawo 2 wosasinthika, wakhungu pawiri, woyendetsedwa ndi placebo kuti awunike chitetezo ndi mphamvu ya Antroquinonol mwa odwala omwe ali m'chipatala omwe ali ndi chibayo chochepa kapena chochepa chifukwa cha matenda a COVID-19 (Coronavirus SARS-CoV-2 matenda). M'malo mwake, kuyesereraku kunaphatikizanso odwala a ICU omwe amafunikira thandizo la okosijeni. Pambuyo pomaliza zowunika zonse ndikukwaniritsa zofunikira, odwala adzalandira 100mg ya Antroquinonol kapena placebo kawiri pa tsiku kwa masiku 14 kuphatikiza ndi Standard of Care (SoC) therapy malinga ndi mfundo za SoC zakomweko. Mlanduwu udamaliza kulemba anthu odwala 124 ku USA, Peru ndi Argentina komwe chipwirikiti chatsopanochi chafalikira ndi mitundu yosiyanasiyana ya SARS-CoV-2.
Deta ya mayeso azachipatala idawulula:
1. Chotsatira Chotsatira Choyambirira: chiŵerengero cha kuchira [Nthawi Yanthawi: Masiku 14]Chigawo cha odwala omwe ali ndi moyo komanso opanda kupuma (mwachitsanzo, palibe chifukwa cha mpweya woipa wa makina, mpweya wosasunthika, mpweya wothamanga kwambiri, kapena ECMO) pa Tsiku la 14. Zotsatira: Mu gulu la Antroquinonol, chiwerengero cha kuchira chinali 97.9% pa tsiku la 14 ulendo. Kuphatikiza apo, palibe imfa kapena kulephera kupuma komwe kunapezeka mu gulu la Antroquinonol patsiku la 28 lochezera ndi kuchira kwa 100%.
2. Zotsatira Zachiwiri:(a) Nthawi Yokhala ICU:Zotsatira: Nthawi yapakati ya ICU kukhala mu gulu la Antroquinonol inali yofupika kwa masiku 9.5 kuposa ya gulu la placebo. (b) Kutalika kwa chipatala [Nthawi Yanthawi: Masiku 28]: nthawi yochotsa odwala.Zotsatira: Kutalika kwapakati pachipatala kunali masiku a 4 mu gulu la Antroquinonol. : Zotsatira zakusintha kwachipatala monga momwe zimayesedwera ndi "WHO COVID-2 Clinical Improvement Ordinal Scale".Zotsatira: Nthawi yapakati kuti mufike pa 28 mu "WHO COVID-19 Clinical Improvement Ordinal Scale" inali masiku 0 mu gulu la antroquinonol.(d) Nthawi yopita ku chilolezo cha virological [Nthawi Yanthawi: masiku 19]: kuyesedwa ngati masiku ophunzirira kuyambira kuchiyambi kwa chithandizo kupita ku mayeso oyamba a SARS-CoV-29 PCR.
Pakuwunika kwachitetezo, zomwe zidawonetsa kuti Antroquinonol adawonetsa kulekerera bwino komanso zotsatira zachitetezo.
