Ngakhale makamaka matenda opuma, COVID-19 yawonetsedwa kuti imayambitsa mayankho osiyanasiyana, kuphatikiza zoyipa pamachitidwe amtima. Odwala ena adawonetsa kuyankha kotupa komwe kungayambitse thrombosis, ndipo pali chiwopsezo chachikulu kwa omwe ali ndi matenda oopsa.
Mu pepala loyamba, ofufuza ku University of Pennsylvania adazindikira oyimira pakati pa kutupa ndi matenda amtima mwa odwala a COVID-19 omwe amalumikizana bwino ndi kuyambitsa kwa mapulateleti mu BioFlux system. Gululi lidawonetsanso kuti Syk inhibitor fostamatinib idasinthiratu kuchuluka kwa mapulateleti pamayesero a BioFlux. Ofufuzawo adatsimikiza kuti izi zikuyimira njira yodziwika, yolunjika yosinthira izi.
Mu pepala lachiwiri, ofufuza a University of Tuebingen adawonetsa kuti kuchepa kwa cAMP (cyclic adenosine monophosphate) m'mapulateleti kumapangitsa kuti ma antibody-induced platelet coagulation komanso kupanga thrombus. Zotsatirazi zidalepheretsedwa ndi Iloprost, wothandizira wovomerezeka wachipatala yemwe amachulukitsa kuchuluka kwa cAMP m'mapulateleti.
Mapepala onsewa adadalira kachitidwe ka BioFlux kuti ayese ntchito ya mapulateleti mwa odwala a COVID-19. Dongosolo la BioFlux limakhala ngati "mtsempha pa chip" womwe umawongolera bwino chilengedwe cha cell kuti titsanzire mikhalidwe yathupi la munthu, ndikupereka nsanja yabwino yofufuza ntchito zamagazi zokhudzana ndi COVID-19. Pogwiritsidwa ntchito m'ma lab oposa 500 padziko lonse lapansi, makina a BioFlux amapezeka m'makonzedwe osiyanasiyana kuti akwaniritse zofunikira za labotale iliyonse. Machitidwe amapezeka ndi kuthekera kosiyanasiyana ndi zotulukapo ndipo amagwiritsidwa ntchito pakufufuza koyambira kudzera mukupeza mankhwala ndi chitukuko cha matenda.
