AffaMed Therapeutics, kampani yapadziko lonse lapansi yazachipatala ya biotechnology yodzipereka kupanga ndi kugulitsa zinthu zosintha zamankhwala, digito ndi maopaleshoni, lero yalengeza kuti United States Food and Drug Administration (FDA) yathetsa ntchito yake ya Investigational New Drug (IND) pa chitukuko chachipatala. AM712 (ASKG712), buku lodziwika bwino la bispecific biologic molecule lomwe limatsekereza zonse za vascular endothelial growth factor (VEGF) ndi angiopoietin-2 (Ang-2) pochiza matenda a retinal vascular.
Pansi pa IND iyi, AffaMed posachedwa ayambitsa kafukufuku wa Gawo 1 ku United States kuti afufuze zachitetezo, kulolerana, pharmacokinetics, komanso mphamvu ya AM712 m'maphunziro omwe ali ndi neovascular AMD.
AffaMed Therapeutics posachedwapa yachita mgwirizano wa laisensi ndi AskGene Pharma Inc. kuti ikhale ndi ufulu wokhawokha wokhazikitsa, kupanga ndi kugulitsa AM712 m'madera omwe kale anali ku Asia kuphatikiza Japan padziko lonse lapansi.
"Ndife okondwa kuyanjana ndi AskGene ndikulandila chilolezo chathu choyamba cha IND kuchokera ku FDA." Dr. Dayao Zhao, CEO wa AffaMed anati: "Monga gawo la njira zathu zatsopano za China-for-Global kuti tithandizire kupezeka kwamphamvu kwa AffaMed ku China ndi US kuti apititse patsogolo chithandizo chamankhwala cham'misika yapadziko lonse lapansi, mgwirizano wa laisensiyi ukulimbikitsanso njira yathu yapadziko lonse ya ophthalmology. . Ndine wokondwa kwambiri kuchitira umboni kuthamangitsa kwathu mwachangu njira iyi kuchokera pakupatsidwa chilolezo kupita ku US IND ndipo ndikuyembekeza mgwirizano wathu wapamtima ndi AskGene. ”
"AskGene yadzipereka kubweretsa mwachangu mankhwala otetezeka komanso othandiza kwa odwala pogwiritsa ntchito umisiri waluso. Ndife okondwa kugwirira ntchito limodzi ndi AffaMed kuti apange anti-VEGF/ANG2 bispecific molekyulu AMG712(ASKG712) kuti apindule odwala" anatero Dr. Jeff Lu, mkulu wa bungwe la AskGene: "Katswiri wapadziko lonse wa gulu la AffaMed m'dera la ophthalmology anali wothandiza kwambiri. zofunika kwambiri pa mgwirizano wathu. Pogwira ntchito limodzi, titha kupititsa patsogolo chitukuko cha ASKG712 padziko lonse lapansi.
Dr Ji Li, Purezidenti wa AffaMed anati: "Timakhulupirira kuti AM712 ili ndi mwayi wokhala ndi anti-VEGF / Ang-2 bispecific bispecific molecule kuti athetse zosowa zachipatala zomwe sizikukwaniritsidwa pakati pa odwala omwe ali ndi matenda a retinal. Ndife okondwa kuwonetsa kuthekera kwathu kochita bwino polandila chilolezo cha US IND mkati mwa miyezi iwiri titamaliza mgwirizano wathu ndi AskGene. "
