Ndi Akuluakulu ati Achichepere Amene Ali Pachiwopsezo Chodwala Khansa ya Colourectal?

Chiwerengero, chiwerengero chapakati pa 0 ndi 1, chimapangidwa kuchokera ku chiwopsezo cha anthu chokhala ndi khansa m'magulu onse a m'mimba pogwiritsa ntchito mitundu 141 ya majini (kusintha kwa DNA code) kofala kwambiri mwa anthu omwe ali ndi matendawa. Izi zomwe zimatchedwa kuti polygenic risk score ndiye zimawonjezedwa ku chiwerengero chofanana cha chiopsezo chotengera zinthu 16 za moyo zomwe zimadziwika kuti zimawonjezera mwayi wa anthu odwala khansa ya m'matumbo, kuphatikizapo kusuta, zaka, komanso kuchuluka kwa fiber ndi nyama yofiira zomwe zimadyedwa.

Chiwopsezo cha khansa ya m'matumbo ndi matumbo chikukwera kwambiri pakati pa achichepere ku United States, komanso mayiko ena ambiri. Ku US kokha, mitengo yawonjezeka chaka chilichonse kuyambira 2011 mpaka 2016 ndi 2% mwa anthu ochepera zaka 50.

Motsogozedwa ndi ofufuza a ku NYU Langone Health ndi Laura ndi Isaac Perlmutter Cancer Center, kafukufuku watsopanoyu adawonetsa kuti omwe ali ndi chiwopsezo chachikulu kwambiri, kapena chachitatu, ophatikizika a polygenetic ndi chiwopsezo cha chilengedwe anali ochulukirapo kanayi kukhala ndi khansa ya colorectal kuposa amuna ndi akazi omwe. adapeza m'munsi mwachitatu.

"Zotsatira zathu zamaphunziro zimathandizira kuthana ndi kuchuluka kwa khansa yapakhungu pakati pa achichepere ku United States ndi mayiko ena otukuka, ndikuwonetsa kuti ndizotheka kuzindikira omwe ali pachiwopsezo chachikulu cha matendawa," akutero wofufuza wina wamkulu Richard Hayes. PhD, DDS, MPH.

Lofalitsidwa mu Journal of the National Cancer Institute pa intaneti Jan. 13, phunziroli linaphatikizapo kuyerekeza kwa akuluakulu a 3,486 osakwana zaka 50 omwe adayambitsa khansa ya m'mimba pakati pa 1990 ndi 2010 ndi 3,890 anyamata ndi atsikana omwe alibe matendawa. Onse anali nawo pa kafukufuku wofufuza anthu omwe ali ndi khansa ku North America, Europe, Israel, ndi Australia.

Hayes, pulofesa mu Dipatimenti ya Population Health and Environmental Medcine ku NYU Grossman School of Medicine, akuchenjeza kuti chida cha gulu lake sichinakonzekere kugwiritsidwa ntchito kuchipatala. Asanavomerezedwe kwambiri, akuti kuyezetsa kwina kumafunikanso pamayesero akuluakulu kuti akonzere chitsanzocho, kufotokoza momwe angagwiritsire ntchito bwino madokotala, ndikuwonetsa kuti, akagwiritsidwa ntchito, njira yolembera imatha kuteteza matenda ndi imfa.

Hayes akuti sizikudziwikabe chifukwa chake kuchuluka kwa khansa ya colorectal ikuchulukirachulukira mwa achichepere. Mosiyana ndi izi, ziwerengero za anthu okalamba zatsika kwambiri chifukwa cha kupita patsogolo kwa kuyezetsa komanso kuchulukitsitsa kwa zotupa zomwe zikuwakayikira asanalowe ku khansa.

Komabe, akuti, khansa ya m’mimba imapha anthu oposa 53,000 chaka chilichonse ku United States. Ndipo ndichifukwa chake bungwe la American Cancer Society ndi malangizo a federal tsopano amalimbikitsa kuyambika kwa chizolowezi chazaka 45.

"Cholinga chathu chachikulu ndikuti tiyeseretu kuti anthu onse adziwe ngati iwo, kutengera chibadwa chawo komanso thanzi lawo, ayenera kuyamba kuyeza khansa yapakhungu," akutero Hayes. Madokotala amafunikira chida chomwe chingagwiritsidwe ntchito kalekale zizindikiro zochenjeza zisanawonekere, monga kupweteka kwa m'mimba, kuchepa kwa magazi, ndi kutuluka magazi m'matumbo.

Kafukufuku waposachedwa adasanthula zomwe zasonkhanitsidwa kuchokera ku maphunziro a khansa 13 ku United States, Canada, United Kingdom, Germany, Spain, Israel, ndi Australia.

Pakadali pano, anthu aku America opitilira 150,000 amapezeka chaka chilichonse ndi khansa ya m'matumbo ndi rectum.