“Ndife okondwa kukwaniritsa cholinga chofunikirachi. Kukwaniritsa izi ndi umboni wa kudzipereka kwathu pakupititsa patsogolo luso la matenda opatsirana, komanso kuthekera kwathu kukwaniritsa zosowa zapadziko lonse lapansi mwachangu, mwamphamvu zasayansi komanso zotsatira zochititsa chidwi, "atero a Rogers Luo, Purezidenti ndi General Manager, Greater China wa Brii Bio. "Monga kampani yoyambira padziko lonse lapansi yaukadaulo yaukadaulo yomwe ili ku China ndi US, tikuyesetsa kupititsa patsogolo mwayi wopeza chithandizochi kwa odwala ambiri a COVID-19 ku China, ndikukulitsanso kuyesetsa kwake kuti agwirizane ndi kufunikira kwa chithandizochi. Njira zochiritsira za COVID-19 kuti athane ndi mliriwu. ”
Chivomerezo cha NMPA chimachokera pa zotsatira zabwino zomaliza ndi zosakhalitsa kuchokera ku mayesero achipatala a ACTIV-2 Phase 3 omwe amathandizidwa ndi NIH ndi odwala 847 olembetsa. Zotsatira zomaliza zidawonetsa kuchepetsedwa kwa 80% (78% pazotsatira zanthawi yochepa) kuchepetsa kugonekedwa m'chipatala ndi kufa ndi kufa kochepa kudzera m'masiku 28 mumkono wamankhwala (0) wokhudzana ndi placebo (9), komanso kuwongolera chitetezo pa placebo m'malo omwe si- Odwala omwe ali m'chipatala a COVID-19 omwe ali pachiwopsezo chachikulu chopita ku matenda oopsa. Miyezo yofananira yofananira idawonedwa mwa omwe adayambitsa chithandizo koyambirira (masiku 0-5) komanso mochedwa (masiku 6-10), kutsatira kuyambika kwa zizindikiro, kupereka umboni wofunikira wachipatala mwa odwala a COVID-19 omwe adachedwa kulandira chithandizo.
M'miyezi yosakwana 20, Brii Bio adapititsa patsogolo kuphatikiza kwa amubarvimab/romlusevimab kuchokera pakupeza mpaka kumapeto kwa chitukuko cha Phase 3 zomwe zidapangitsa kuti avomerezedwe mwachangu ndi NMPA. Chivomerezochi chikuyimira mgwirizano wopambana kwambiri ndi asayansi apamwamba komanso ofufuza zachipatala ku China komanso padziko lonse lapansi pa ntchito yomwe adagawana, kuphatikizapo 3rd People's Hospital of Shenzhen ndi Tsinghua University, omwe adapeza kuti ma antibody amatsogolera; U.S. National Institute of Health (NIH), AIDS Clinical Trial Group (ACTG), yomwe inathandizira ndi kutsogolera mayesero a ACTIV-2.
"Monga chithandizo choyamba cha COVID-19 ku China, kuphatikiza kwa amubarvimab/romlusevimab kumawonetsa zotsatira zabwino zachipatala komanso chitetezo chabwino pamayesero apadziko lonse lapansi, osiyanasiyana. Ndilo gulu lokhalo lokhalokha la antibody padziko lonse lapansi lomwe lili ndi mphamvu zotsimikizika zachipatala pakati pa odwala omwe ali ndi mitundu yosiyanasiyana ya SARS-COV-2 pamayesero ofunikira kwambiri asanayambe kutsatsa, "anatero Prof. Linqi Zhang, Mtsogoleri wa Global Health and Infectious Diseases Research Center ndi Comprehensive AIDS. Research Center ku School of Medicine University Tsinghua. "Kuphatikizika kwa antibody kunapereka chithandizo chapadziko lonse lapansi ku China kuti athane ndi mliri wa COVID-19, womwe ukuwonetsa bwino zomwe takumana nazo, nkhokwe zasayansi ndiukadaulo, komanso kuyankha kwathu komanso kuthekera kwathu polimbana ndi matenda opatsirana ndikuthandiza kwambiri popewa. ndikuwongolera mliri ku China ndi padziko lonse lapansi. Ndife okondwa kuyanjana ndi 3rd People's Hospital of Shenzhen ndi Brii Bio pakupeza, kafukufuku wachipatala, ndi kafukufuku womasulira wa mankhwala ophatikizana ndipo potsirizira pake tidakwanitsa izi. Tipitiliza kuwunika kugwiritsa ntchito kuphatikiza kwa amubarvimab/romlusevimab pakati pa anthu omwe alibe chitetezo chamthupi ngati njira yowonjezerapo yothandizira.
"Kuyambira pomwe mliri wa COVID-19 udayamba, mfundo yathu yakhala njira yozikidwa pa sayansi pamene tikupitiliza kulimbana ndi mliriwu. Gulu lathu lofufuza lidapeza ma antibodies awiri omwe amagwira ntchito kwambiri kuchokera kwa odwala omwe ali ndi COVID-19, omwe adayala maziko olimba opangira kuphatikiza kwa amubarvimab / romlusevimab motsutsana ndi COVID-19, "atero a Lei Liu, Director wa National Clinical Research Center for Infectious Diseases ku. Shenzhen ndi Secretary Party wa 3rd People's Hospital of Shenzhen. "Ndife okondwa kuyanjana ndi Prof. Linqi Zhang waku Tsinghua University ndi Brii Bio kuti apereke ukadaulo wathu ndipo ndife onyadira kupereka chithandizo choyamba cha China cha COVID-19 panthawi yomwe mliriwu ukupitilirabe."
